Science refers to the construction of knowledge by using the scientific method. This method is based on empirical evidence.
Science can be defined as the construction of knowledge (scientific knowledge) by using the scientific method.
The scientific method includes several sequential steps:
- Observation
- Ask questions
- Form a testable explanation (hypothesis)
- Test the hypothesis
- Collect results (empirical evidence)
- Draw conclusions
In the scientific method, empirical evidence can be used to support the working hypothesis.
Learn more about the scientific method here:
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the answer is wind and the earths rotation
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It generally complained of flu-like symptoms (headache, fever, muscle pain, sore throat) followed closely by stomach pain, vomiting, and diarrhea, which sometimes progressed to the bruising and hemorrhaging that he was seeing in his current patient.
Answer:
(C) Aminoacyl-tRNA synthetases have an additional active site that binds to non-cognate tRNAs. The tRNAs that bind to this second active are hydrolyzed and released from the enzyme.
Explanation:
In case of translation, proof reading is done by aminoacyl-tRNA synthetases only. Aminoacyl-tRNA synthetases have two mechanisms to avoid error during translation which are mentioned as under:
<u>(1) Chemical proof reading:</u> Incorrect amino acids rather than being hydrolyzed in catalytic pocket get hydrolyzed in editing pocket and thus they hardly get attached to tRNA.
For example: For distinguishing similar amino acids like isoleucine and valine, isoleucyl-tRNA synthetase uses a second active site which is meant for only valine not for isoleucine. In this particular site, valine which had entered the enzyme is cleaved away with the help of editing reaction after which the enzyme is well prepared to process isoleucine which is the correct amino acid for this enzyme.
<u>(2) Kinetic proof reading: </u>Even if an incorrect amino acid has entered a particular aminoacyl-tRNA synthetase, it does not cause appropriate conformational change in the enzyme because of which the incorrect amino acid loosens from the enzyme and does not get incorporated.
Note: In this example, only chemical proof reading is mentioned not kinetic proof reading.
In meiosis, one diploid cell divides to make four haploid cells.
