The same ligand can bind to different receptors causing different responses (e.g.. acetylcholine). On the other hand, different ligands binding to different receptors can produce the same cellular response (e.g. glucagon, epinephrine).
Sexual gratification is the act of pleasing or satisfying one's sexual urges or others'. One of its kind is sexual sadism which is a sensual and sexual gratification derived from inflicting pain on a victim or seeing their victim suffer. It is a paraphilic coercive disorder wherein it inflicts continuous harm upon its victim even without the latter's compliance which sometimes lead not only to his/her eventual death but also defacement of his/her body.
The cycle of heating, rising, cooling and sinking is called a convection current. These currents are caused by the very hot material at the deepest part of the mantle rising, then cooling, sinking again and then heating, rising and repeating the cycle over and over.
