A transient shortage of oxygen (global ischemia) releases excess glutamate into the extracellular fluid of the brain. This cause

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A transient shortage of oxygen (global ischemia) releases excess glutamate into the extracellular fluid of the brain. This cause

s neuronal death by hyperexcitation to a greater extent in the hippocampus than in the cortex. Which reason best explains why the hippocampus is selectively vulnerable during global ischemia?

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1 answer:

Maru [420] · Answer 1 · 2021-12-14T14:01:35+03:00

Answer:

Explanation:

The hippocampus becomes selectively unprotected because the receptor of the NMDA becomes more pronounced in the hippocampus than in the cortical neurons and this leads to a situation where by the hippocampus becomes more exposed to extracellular glutamate whose release is in excess.