The most common drug that causes drug-induced hepatitis is Paracetamol (in other countries, Acetaminophen). Paracetamol overdose overwhelms the liver's drug detoxifying capacity and produces a toxic metabolite <span>N-acetyl-p-benzoquinone imine or NAPQI which is responsible for the hepatitis. </span>
No I have not completed it but, I'd be happy to help you with any other questions you might have.
Answer:
A lethal mutation, thereby the resulting phenotype is not observed
.
Explanation:
Lethal mutations are the result of genomic changes that may be lethal in certain conditions. In genetic research, this type of mutation has shown to be very useful in analyzing gene function (i.e., genes whose protein products are key for the survival of the organism in question), and they are perfect gene markers. In bacteriophages, for example, temperature-sensitive mutants of phage T4 that can not grow at temperatures higher 42°C have been identified (Edgar & Lielausis 1964).
Citation:
R. S. Edgar, & I. Lielausis (1964). Temperature-sensitive mutants of bacteriophage T4D: their isolation and genetic characterization. Genetics, 49(4), 649.
