1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
riadik2000 [5.3K]
3 years ago
13

Nuclear hormone receptors form a complex with their ligands, other proteins, and DNA control elements in order to regulate the e

xpression of specific genes. These nuclear hormone receptors have four principal domains. Categorize each trait according to the appropriate nuclear hormone receptor domain with which it is associated.
Biology
1 answer:
ArbitrLikvidat [17]3 years ago
5 0

Answer:

Explanation:

Nuclear receptors are a type of protein that functions as an intracellular steroid and thyroid hormone receptor. The interaction of these hormones in conjunction with nuclear receptors changes the pattern of gene expression, allowing certain genes to be transcribed while others are silenced.

As a consequence, unique mRNA translation products, proteins, and, in most cases, enzymes are generated. Nuclear receptors connect to DNA directly and control the expression of certain genes, regulating the organisms growth, homeostasis, and metabolism.

The following domains are found in a normal nuclear receptor:

The amino-terminal activation domain contains the transcriptional activation mechanism and is strongly variable in sequence (AF1). The recruiting of coregulators is the domains key feature.

⇒ Activation function 1 (AF1); Coregulator recruitment

DNA binding domain: It is amongst the most closely conserved centrally located domains, with two zinc fingers that attach to specific DNA sequences known as hormone reaction components (HRE).

⇒ nine conserved cysteine residues; zinc finger domain; center of the receptor.

The hiinge domain serves as a versatile connection between the DNA binding and ligand-binding domains. It has a nuclear localization signal in it. ⇒ Nuclear localization signal

Ligand binding domain:  The sequence of the ligand-binding domain is moderately conserved throughout nuclear receptors. It denotes the carboxyl-terminal end of a ligand domain. It has hydrophobic steroid-binding pockets that draw the hormone and AF2 activation domains. It also attaches to proteins that serve as coactivators and corepressors.

⇒ binding of corepressor proteins;  steroid-binding hydrophobic pocket; AF2 activation domain; binds coactivators; carboxyl-terminal end

You might be interested in
Tsunami waves flood coastal and inland areas and affect coastal life. Which of these properties of tsunami waves most contribute
Ede4ka [16]
I found the exercise on the internet and here are the options:
"<span>the low friction of waves at the shoreline
the high friction of waves at the shoreline
the high amplitude of the waves at origination
the long wavelength of the waves at origination"

The tsunami property that most contributes to the flooding is "the long wavelength of the waves at origination". The long wavelength that the tsunamis have at their origin makes so that when the wave reaches the shore, instead of a normal spreading, a much longer spreading takes place taking the ocean as far as the wavelength allows.</span>
7 0
3 years ago
Explain the process by which an attack of hay fever follows exposure to pollen
Bezzdna [24]

<span>Hay fever is a manifestation of allergic reaction from pollen, which is prevalent during haying season. Hay fever is commonly known as allergic rhinitis caused by an oversensitive immune system, particularly the lymphocytes, leading to a misdirected immune response. The body undergo a sensitization when one develops IgE antibodies and develop a strong TH2 response against pollen. Then, this newly develop IgE antibodies sticks to basophils and mast cells with no signs and symptoms yet. However, when one is expose again to pollens, mast cells will be activated and release mediators who are responsible for immediate vascular and smooth muscle reaction. After this, local clinical manifestation of hay fever will be observed. </span>

4 0
3 years ago
How does exercise affect blood flow?
gulaghasi [49]

Answer:

Exercise strengthens your heart and improves your circulation. The increased blood flow raises the oxygen levels in your body. This helps lower your risk of heart diseases such as high cholesterol, coronary artery disease, and heart attack. Regular exercise can also lower your blood pressure and triglyceride levels.

Explanation:

4 0
3 years ago
The French biologist Lamarck hypothesized that “organisms could acquire traits making them better adapted to their environment a
adell [148]

Answer:

Darwin suggests that the strongest survive and adapt to produce even stronger more adaptable offspring

8 0
3 years ago
i need someone that knows history and everything about slavery to repsond ASAP will give branliest for the best answer
Alborosie

Answer:

i know some whatcha need?

Explanation:

8 0
2 years ago
Other questions:
  • Can anyone explain the development stages of foetus in ownwords/understanding?
    11·1 answer
  • They are exitable cells that are long and fibrosis. These cells are ready for contraction or the activation of tension for the m
    15·1 answer
  • Cell membranes are said to be selectively permeable. Which statement best explains what selectively
    11·2 answers
  • How are gametes and zygotes related
    7·1 answer
  • Carolus Linnaeus wanted to classify the hibiscus flower. He began by examining the color of the flower, its petal shape, its pet
    6·1 answer
  • What are two mainly body cavities?
    5·2 answers
  • Name the factors that can influence influence the reaction time of the driver?
    15·1 answer
  • With the current energy shortage, nuclear energy can been seen as: a hazard a solution A and B neither A nor B
    15·2 answers
  • Please help me with this
    7·2 answers
  • Is it possible for social experience to make someone homosexual, or are homosexuals born with such a tendency? Then discuss how
    13·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!