The correct answer would be D) decomposers. Decomposers do just what they're named for. Decompose things. They break down dead plant and animal material, gaining nutrients from it, while releasing CO2 into the atmosphere.
Answer:
Human insulin protein will not be produced
Explanation:
For production of human insulin protein in bacteria, first the insulin gene needs to be transcribed to corresponding mRNA. This mRNA will be then translated to produce insulin protein. The initial portion of any gene has a promoter sequence. During transcription RNA Polymerase recognizes this promoter sequence to initiate the process.
Here, the gene's first five nucleotides were accidentally cut out so now the promoter sequence has been altered. RNA Polymerase will not be able to recognise it so transcription will not occur. No mRNA will be formed and as a result translation will also not occur and there will be no production of insulin protein.
So Male is AB
and Femlae is AO
so on crossing there ;
........A ......O
A....AA... AO
B ...AB... BO
So genotypes ; AA , AO , AB, BO
And phenotypes; Blood types A, AB , B
*used dots in punnet as i do not get proper spacing !!
In 15 patients with severe congenital ADAMTS-13 deficiency (plasma ADAMTS-13 activity 6%), the safety, tolerability, and pharmacokinetics of recombinant ADAMTS-13 were examined.
What is pharmacokinetics?
Pharmacokinetics (PK) is the study of how the body responds to drugs over the full exposure period (medications for the sake of this article). Pharmacodynamics, which closely evaluates the drug's impact on the body, is closely related to this yet clearly distinct from it. Absorption, distribution, metabolism, and excretion are the four primary variables this field often evaluates (ADME). Understanding these processes gives medical professionals the freedom to recommend and deliver drugs that will have the most benefit and the lowest danger, as well as to make adjustments as needed in light of the diverse physiology and lifestyles of their patients.
No significant side effects and no anti-ADAMTS-13 antibodies were found. BAX 930 was well tolerated. Adolescents and adults that received a single dose of BAX 930 at 5, 20, or 40 U/kg body weight showed approximately dose proportional maximum plasma concentration (Cmax [U/mL]) and area under the concentration-time curve (AUC [hU/mL]). Individual ADAMTS-13:Ag and activity levels increased in a dose-related manner and peaked within an hour. A dose-dependent persistence of von Willebrand factor (VWF) cleavage products caused by ADAMTS-13 and a smaller VWF multimeric size were seen with increasing BAX 930 dosages. It was shown in this investigation that BAX 930's pharmacokinetic parameters were similar to those predicted in earlier plasma infusion trials and that pharmacodynamic activity was present.
Complete Question
Recombinant ADAMTS-13: first-in-human pharmacokinetics and safety in congenital thrombotic thrombocytopenic purpura
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