Pretty confident that it is A, judging by that the word composition is used as a combination or a ratio of 2 things. Also none of the other options make sense.
Answer:
Melanoma signs and symptoms
Explanation:
A large brownish spot with darker speckles.
A mole that changes in color, size or feel or that bleeds.
A small lesion with an irregular border and portions that appear red, pink, white, blue or blue-black.
A painful lesion that itches or burns.
The root neuro means nerve or referring to the nervous system.
Hope this Helps!!