Question

PFK can be allosterically inhibited by ATP at high concentrations. Which of the following is the benefit of regulating glycolysis by the concentration of ATP?

Answer 1

Answer:

The principle benefit of regulating glycolysis by the concentration of ATP is to signals the cell to stop glycolysis as sufficient amount of ATP is already present in the biological system.

Explanation:

Phosphofructokinase 1 is allosterically inhibited by ATP.Glycolysis is a catabolic as well as exergonic process which deals with the oxidation of glucose to form pyruvate along with ATP molecules.

            When ATP is present at high concentration within our body at that time there is no need to synthesize additional ATP because ATP is already present in sufficient amount.

       To maintain its own homeostasis ATP allosterically inhibit the catalytic activity of phosphofructokinase. As a result glycolysis is inhibited and the glucose molecule can be utilized in other metabolic pathways.