Answer:
Blood pressure forces plasma minus its macromolecules (e.g., proteins) from the glomerular capillaries into the Bowman's capsule, which is continuous with the proximal convoluted tubule.
Chromatin during interphase is in it's most loosely condensed state and is spread through-out the nucleus
In the lock and key model of enzyme action, the substrate fits into the active site of the enzyme, then after undergoing a conformational change, it will release the substrate and produce a product.
Hope this helps :)
https://www.immunology.org/public-information/bitesized-immunology/cells/cd8-t-cells