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Leto [7]
3 years ago
14

A mechanism by which cancer cells can evade an immune response involves an alteration in the amount of MIC on the cell surface b

y _________. Group of answer choices cleavage of MIC at the cell surface by a protease decreasing the level of MIC transcription switching from a transmembrane form of MIC to a secreted form cytosolic degradation of MIC in proteasomes alternative mRNA splicing resulting in a truncated form of MIC that is no longer able to bind to NKG2D
Biology
1 answer:
kvasek [131]3 years ago
8 0

Answer:

cleavage of MIC at the cell surface by a protease

Explanation:

The immune system refers to a complex network of cells and proteins that function to eliminate potentially tumorigenic cells on a daily basis. However, cancer cells show mechanisms in order to escape immune responses. MHC class I chain-related proteins A and B (MICA and MICB) are expressed in normal and tumorigenic cells where they act as ligands of the NKG2D receptor. The expression level of these proteins (MICA and MICB) is finely regulated by the activity of metalloproteinases (i.e., by protease-mediated cleavage), but this mechanism is altered in cancer cells. Recently, drug therapies that stimulate NKG2D mediated tumor destruction by reducing the cleavage of MICA and MICB from the surface of cancer cells have been developed.

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Findings show that short-term changes in inhibitory control are predictive of alcohol consumption, which raises the possibility that temporary changes in inhibition may be a risk factor for periods of severe drinking.

<h3>What is inhibitory control?</h3>
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Learn more about the inhibtory control with the help of the given link:

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If a cell is placed in an isotonic solution, water will ____?
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3 0
3 years ago
Read 2 more answers
1. Explain how the traits of an organism are related to the genes in DNA.
viktelen [127]

Genes in DNA or responsible for the traits an organism has. This is caused by Dominant and Recessive Traits. Remember that Genotypes are the genetic letters such as RR, Rr, and rr. Phenotype is physical traits.

Dominant Traits are more likely or always show in the offspring. The Dominant Genotype uses Capital letters such as RR.

Recessive Traits are less likely to show up. Their Genotype use lower case such as rr. Now genotypes of Rr have one dominant trait and one recessive trait. If the dominant trait was black fur and the recessive white fur, the offspring will be black fur because dominant traits overpower the other.

To understand how to know if an organism will have Dominant or Recessive Genes, you have to use something called a Punnet Square. Lets imagine 2 parents both have the genotype Rr. R is Black fur and r is white fur. As you can see from the chart, 3 of 4 boxes have Rr and 1 rr. Since there is a Dominant Trait with a Recessive, they will show a Dominant Phenotype, or Black fur. This has 3/4 chance and a 1/4 chance for white fur in the offspring.

| R. r

-----------------------------------

R | Rr. Rr

-----------------------------------

r | Rr. rr

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