<span>In 1944, Oswald Avery identifies DNA (Deoxyribonucleic Acid) as transforming principles. This famous genetic scientist has made great efforts for many steps to find what happened after combinations of some bacteria. After purification, he found a new substance which was a nucleic acid, involving the discovery of DNA after further analysis.</span>
The marine biome is the largest on Earth
The activation energy needed for the chemical reaction decreased by an Enzyme.
Activation energy is the amount of energy required in a chemical reaction.
Enzymes lowers the activation energy by increasing the rate of reaction.
The energy required for a reaction to start is called activation energy. Enzymes are proteins that lower the activation energy of a reaction. In doing this, enzymes increase the rate of a reaction, helping it to occur faster. However, enzymes are not consumed in a reaction; they simply help it to occur.
Answer:
soil temperature soil nutrients soil ph
Answer:
by designing a drug with steric effects on BCR-ABL1
Explanation:
Chronic myeloid leukemia (CML) is a type of cancer that affects the bone marrow and blood cells. CML is characterized by the formation of the Philadelphia chromosome, a product of a reciprocal translocation between chromosomes 9 and 22. As a consequence of this translocation, an oncoprotein tyrosine kinase called BCR-ABL1 is formed. This protein (BCR-ABL1) is responsible for 95% of all CMLs. In this case, it is possible to inhibit BCR-ABL1 (and thus inhibit CML cell proliferation) by using a kinase inhibitor. Kinase inhibitors are drugs that inhibit kinase function by preferentially binding to the inactive conformation of the target enzyme. These proteins are used to treat cancer by blocking a functional site on the kinase, thereby inhibiting its function. Moreover, it is known that steric effects alter the mode and rate by which a drug interacts with a given target. In this case, a small molecule with steric effects on BCR-ABL1, i.e., capable of altering the shape (conformation) and reactivity of BCR-ABL1, might also be used to selectively inhibit BCR-ABL1.
