Colchicine is a drug that can prevent the formation of microtubules. By blocking the synthesis of spindle microtubules, it will stop mitosis in cell division.
A traditional anti-mitotic medication called colchicine prevents mitotic cells from dividing during metaphase. It forms tubulin-colchicine complexes with soluble tubulin in an imperfectly reversible way, which bind to the ends of microtubules to stop the elongation of the microtubule polymer.
Colchicine is an alkaloid from the Colchicum autumnale plant that prevents microtubule polymerization, which is thought to be necessary for collagen production. This substance is therefore thought to function as an antifibrotic substance by inhibiting collagen production and deposition.
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Answer:
One reason is because of a gender gap. For example, if a someone (a women) collapse on the ground and isn't breathing, studies do show that women are most likely to die and not receive CPR because of their gender.
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--Jay
The experiment was doomed to failure from the beginning. General Carleton’s illusion that the Bosque Redondo would spawn a farming community of thriving transplanted Native American prisoners was disastrous.General Carleton was a strict taskmaster however, and although the Native American prisoners were sick, ill-fed and unfit for heavy manual farm labor, and fields were improperly irrigated, he nearly realized his dream of a bountiful harvest. By mid-summer 1863 the corn alone was expected to yield twenty-five to thirty bushels per acre, a minimum of 75,000 bushels. Considering the extraordinary handicaps under which the Indians worked, this was an astonishing accomplishment. <span>When it seemed Carleton would realize his dreams, nature dealt a lethal blow. The reservation’s 3,000 acres of planted agricultural land was struck by an inch-long cut worm, or “army worm”, that destroyed the crops. The following year, another promising crop was again insect-infested and destroyed. Demoralized, the Indians would refuse to plant again.</span>
