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topjm [15]
3 years ago
10

Consider a cell in which Cl- distributes passively across the membrane according to the membrane potential. The resting membrane

potential in this cell is measured to be -60 mV. If the extracellular Cl- concentration is 100 mM, then the intracellular Cl- concentration is:
Biology
1 answer:
UNO [17]3 years ago
4 0

Answer:

1000 mM

Explanation:

Using V = -60 mV㏒₁₀[K/K'] where V = membrane potential = -60 mV, K = intracellular concentration = unknown and K' = extracellular concentration = 100 mM

So, V = -60 mV㏒₁₀[K/K']

-60  mV = -60 mV㏒₁₀[K/K']

dividing both sides by -60mV, we have

-60  mV/-60 mV = ㏒₁₀[K/K']

㏒₁₀[K/K'] = 1

taking antilogarithm of both sides, we have

[K/K']  = 10¹

multiplying both sides by K', we have

K = 10K'

K = 10 × 100 mM

K = 1000 mM

So, the intracellular Cl- concentration is 1000 mM

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The phenotypic variance= 2113

The eenvironmenal variance= 644

The genetic variance= 1469

The broad-sense heritability = 0.695

Explanation:

To determine the phenotypic variance, we need to know the calculate the environmental variance and the genetic variance first;

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V(p) = V(e) + V(g)                  

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Therefore, Environmental variance can be defined as a portion of phenotypic variance due to differences in the environments to which the individuals in a population have been exposed. The total amount of variance observed is dependent on the genetic component, determined by the variation that is inherited.

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V(e) = (311 + 333) = 644

Genetic Variance simply refer to the variance that occurs or preferrably , that is observed after inbreeding (i.e Variance of F1 = 316  and Variance of F2 = 1153)

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Now, back to phenotypic variance = V(e) + V(g)

substituting the parameters we have;  1469 + 644 = 2113

Broad-sense heritability can be calculated as the ratio of total genetic variance to total phenotypic variance.

= V(g)/ V(p)

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= 0.695

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3 years ago
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