Answer:
The potential mother would be wasting her body's energy and resources constantly producing milk without using it to feed her baby, requiring for her to attain more energy, where she could have just waited until she actually gets pregnant and then start producing milk for her baby once it is close to being or already born.
The plasma membrane or the cell
membrane is the one that protects the cytoplasm of a cell. It is mostly
composed of lipids and proteins. It has a phospholipid bilayer that controls
the entering and exiting of molecules in the cell and at the same time,
provides protection for the cell or plasma membrane. It has polar head and a
nonpolar tail. Proteins embedded within the phospholipid bilayer have the same
function of the plasma membrane that includes selective transport. The
phospholipid bilayer consists mainly of the lipid molecules.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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