Cadherin proteins help animal cells stick (adhere) to each other. Choose which statement about cadherin in cancer cells that are
metastasizing (spreading) throughout a patient's body is most likely correct. 19) A) Cadherin proteins in metastasizing cancer cells are likely to have mutations that make them less "sticky B) Mutations in cadherin proteins are unlikely to affect the metastasizing of cancer cells C) Mutations in cadherin proteins accumulate at a constant rate that can be measured by a molecular clock D) Cadherin proteins in metastasizing cancer cells are likely to have mutations that make them more "sticky"
The answer is : a) Cadherin proteins in metastasizing cancer cells are likely to have mutations that make them less "Sticky".
Explanation:
Cell-cell adhesion is mediated by cadherins that regulate contact formation and stability between cells and thus are important for tissue morphogenesis and homeostasis. Cadherin (more specifically, E-Cadherin) loss of function is thought to enable metastasis due to the impaired intercellular contacts that could lead to increased motility and eventually to invasion and colonization of surrounding tissues.
