Answer:
Activation of infectious inflammation:
PAMPs are derived from microorganisms and thus drive inflammation in response to infections. After identifying microorganisms infections PAMPs by PRRs, activate cytoplasmic complexes called inflammasomes.
After activation of inflammasomes, these inflammasomes activate the protease caspase-1, which then cleaves or breaks various pro-inflammatory cytokines, resulting in maturation and cellular release that cause inflammatory reactions.
lolololololololololololololololololololololololololololololololololol!!
Answer:
Explanation:
When osteocytes were experimentally destroyed, the bones showed a significant increase in bone resorption, decreased bone formation, trabecular bone loss, and loss of response to unloading. ... The osteocyte is an important regulator of bone mass and a key endocrine regulator of phosphate metabolism.
