<span>Amino acids are
weak acids that have at least 2 pka values. They have two titratable protons
that composed of alpha carboxyl (-COOH) and alpha amino (-NH3+), but some amino
acids have a third titratable protons with ionizable groups in the R side chain.
In addition, the structure of amino
acids in peptides and proteins are determined by the charges of the titratable
group and by the R group. </span>
The correct answer is A. the change in pH affects the shape and function of the enzyme. It can only function properly in its optimal pH range.
Enzymes are protein molecules and they have a specific shape, which is altered by temperatures and pH that are not within the enzyme's range of operation. This is because the temperature and pH alter the enzyme's structure, which means the shape of its active site is changed and its substrate is not able to fit inside the active site of the enzyme molecule.
Answer:
please mark as brainliest answer as it will also give you 3 points
Explanation:
Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.[1] They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. In fact, yeast cells can proliferate normally when their CDK gene has been replaced with the homologous human gene.[1][2] CDKs are relatively small proteins, with molecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain.[1] By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase but its activity can be typically further modulated by phosphorylation and other binding proteins, like p27. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.[1] The consensus sequence for the phosphorylation site in the amino acid sequence of a CDK substrate is [S/T*]PX[K/R], where S/T* is the phosphorylated serine or threonine, P is proline, X is any amino acid, K is lysine, and R is arginine.[1]
