Answer and Explanation:
The manipulation of the gene is called genetic engineering. In genetic engineering, fragments of genes are cloned by leading the genes into the host cell. The advantage of using a prokaryotic host system in genetic engineering is that bacterial cells are used to produce commercially significant products. For example, human growth hormone helps to treat dwarfism, and human insulin production, which is used to treat diabetes. The bacterium P.putida is created by genetic engineering, which is used to break down petroleum products. Genetic engineering also carries some potential risks, such as transferring the selected gene into another speice, benefit one species can harm another speice. Therefore genetic engineering must be used in limit in prokaryotes. These limitations are also addressable in single-cell eukaryotic systems. Biologics-based therapeutic medicines such as a vaccine, gene therapies, and cell therapies known as bioproduction are produced. Medicines are so complex that they can only be formed in a living system. Biopharmaceuticals, value-added food, fuels, chemicals, antibiotics, and many other products are produced by bioproduction.
Give brainiest answer Cus like look at my answer
=UrM0MG4Y
<span>Rhabdomyolysis constitutes a common cause of acute renal failure and presents paramount interest. A large variety of causes with different pathogenetic mechanisms can involve skeletal muscles resulting in rhabdomyolysis with or without acute renal failure. Crush syndrome, one of the most common causes of rhabdomyolysis presents increased clinical interest, particularly in areas often involved by earthquakes, such as Greece and Turkey. Drug abusers are another sensitive group of young patients prone to rhabdomyolysis, which attracts the clinical interest of a variety of medical specialties.
We herein review the evidence extracted from updated literature concerning the data related to pathogenetic mechanisms and pathophysiology as well as the management of this interesting syndrome.
Keywords: Rhabdomyolysis, acute renal failure, myoglobin, crush syndrome
The first case of the crush syndrome, which constitutes one of the main causes of rhabdomyolysis, was reported in Sicily in 1908, after an earthquake1,2. In 1930, in the Baltic area, an epidemic of myoglobinuria was observed due to consumption of contaminated fish. Interest in rhabdomyolysis and crash syndrome was stimulated during the World War II particularly after the bombing in London, where the victims developed acute renal failure and myoglobinuria1.
Rhabdomyolysis is a rupture (lysis) of skeletal muscles due to drugs, toxins, inherited disorders, infections, trauma and compression3. Lysis of muscle cells releases toxic intracellular components in the systemic circulation which leads to electrolyte disturbances, hypovolemia, metabolic acidocis, coagulation defects and acute renal failure due to myoglobin4.
The skeletal muscle consists of cylindrical myofibrils, which contain variant structural and contraction proteins. Actin and myosin, arranged in thin and thick filaments respectively, form the repeated functional units of contraction, the sarcomeres5. The sarcoplasmic reticulum constitutes an important cellular calcium storage. It is structurally connected to the t-tubules, that are formed by invaginations of the muscle cell plasma membrane, the sarcelemma, around every fibril (Figure 1). After the sarcelemma depolarization, the stimulation arrives, through the t-tubules junctions, at the sarcoplasmic reticulum, inducing the calcium ions release and triggering muscle contraction6.</span>
Answer:
The last one: dinosaur footprints preserved in mud turned to rock
Fossils have to be physical remains of an animal.
Hope this helps!
