Translation is a complex process that translated the genetic information from the language of DNA in the language of RNA. The first step in this process is the binding of the initiator tRNA (that is bound to the aminoacid methionine) to the small ribosomal unit. Then, the small ribosomal unit joins the mRNA; it is the part of the ribosome mainly responsible for translating. After that, the initiator tRNA binds to the start codon. This reaction frees some initiation factors that make large ribosomal units bind to the small one. Hence, <span>the large ribosomal subunit completes the initiation complex afterwards. The role of the large ribosomal unit is mainly to make the peptidic bonds between the aminoacids in the new protein. After that, </span><span>amino acids are paired with anticodons, gradually forming a long chain</span>; this chain is called a polypeptide and is the skeleton of the protein that is created. Finally, this process stops when one of the three possible stop codons are reached.
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Aminoacyl-tRNA synthetases recognize their specific amino acid by charge, size and R group and recognize the tRNAs that carry it by the nucleotide sequence .
Aminoacyl-tRNA synthetases are enzymes that attaches the appropriate amino acids on to its tRNA . These are also responsible for performing the first step of protein synthesis.
