decomposition of what was alive then the remains are buried by sediments which results in fossilization
The core
Hope this helps it’s been soo long
Natural selection is a factor of evolution that occurs when natural disasters or organisms moving to another place cause the gene pool to shrink
Loss in motor control
Tranquilizers used for sedation, such as Seconal or Nembutal, affect the central nervous system and look to decrease the person's muscular activity. This leads to decreased motor control. Contrarily, anxiety relieving tranquilizers, such as Valium and Xanax, do not cause as severe a loss in motor control but leave stronger effects of aggression.
Answer:
Several 2',3'-dideoxy-3'-thiapyrimidine nucleosides were studied for their ability to inhibit hepatitis B virus (HBV) DNA replication in a HBV-transfected cell line (2.2.15). 2',3'-Dideoxy-3'-thiacytidine (SddC) and 5-fluoro-2',3'-dideoxy-3'-thiacytidine(5-FSddC) were found to be the most potent anti-HBV compounds of those examined. Both compounds resulted in nearly complete cessation of viral DNA replication at 0.5 microM, as monitored by the absence of both intracellular episomal and secreted viral DNAs. The HBV-specific RNAs were not reduced at concentrations that completely blocked HBV DNA replication, suggesting that the inhibitory target is HBV DNA synthesis. The antiviral action of SddC and 5-FSddC was reversible. The concentration of SddC and 5-FSddC required to inhibit 50% of 4-day cell growth in culture was 37 microM and more than 200 microM, respectively. Unlike 2',3'-dideoxycytidine, these two compounds do not affect mitochondrial DNA synthesis in cells at concentrations lower than that required to inhibit cell growth. In view of the potent and selective antiviral activity, both SddC and 5-FSddC should be further evaluated for the treatment of human HBV infection.
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