Classical conditioning is the process of linking two stimuli to produce a response. There are 3 phases for classical conditioning:
Phase 1 (before conditioning): During this phase an unconditioned stimulus is paired to produce an unconditioned response. An unconditioned response naturally triggers a response.
Phase 2 (During conditioning): This phase involves pairing a neutral stimulus with an unconditioned stimulus so that the neutral stimulus becomes the conditioned stimulus. The neutral stimulus does not naturally trigger a response.
Phase 3 (after condition): In this phase only the conditioned stimulus is presented to produce a conditioned response. The conditioned response triggers a response after pairing with an unconditioned stimulus
P 16 does not appear to play a role in blocking cell cycle entry by fibroblast. cyclin dependdent kinase (CDK) promotes cell cycle progression thus inhibitors of CDK inhibit cell cycle. In graph, it has been shown that in absence of p 16 there is no increase in DNA Content but when others are absent ,DNA CONTENT IS MORE.