Some normal cells such as hair follicles cells, mouth cells, digestive tract cells, and bone marrow cells divide rapidly. In mammalians, hair follicle cells are cells localized in the skin, specifically in the dermal layer of the skin. In this region, epidermal cells that form the root of the hair divide rapidly by interacting with neuropeptides, hormones, and immune cells. On the other hand, the bone marrow is a spongy tissue found in bones that contain stem cells (which also divide rapidly). In consequence, it is well-known that high-dose chemotherapy treatments may damage these types of cells.
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