Answer: DF508 mutation. A Genetic, Hereditary, Autosomal and Recessive Mutation.
Explanation:
Cystic fibrosis (CF) is a recessive autosomal lethal disease, it is most common on Caucasoid populations. Its diagnosis is suggested by the clinical features of chronic obstructive pulmonary disease, persistent pulmonary colonization (particularly with mucoid Pseudomonas strains), meconium ileus, pancreatic insufficiency with or familiarity history of the disease. The FC gene is large, with about 250 Kb of genomic DNA, 27 exons representing about 5% of genomic DNA; encodes a 6.5 kb transcribed mRNA. This mRNA is transcribed into a protein of 1480 amino acid called CFTR (Regulator Transmembrane Conductance Cystic Fibrosis). When a three-base pair deletion, adenosine-thymine-thymine (ATT) identified in the CFTR gene, exon 10, it results in the loss of a single amino acid phenylalanine at position 508 of the protein. This mutation is called DF508; “D” stands for deletion and “F” for phenylalanine amino acid.
The shuffling of chromosomes that occurs during both fertilization and meiosis can lead to genetic variation. This is because of the independent assortment and crossing over. Hope this answers the question. Have a nice day. Feel free to ask more questions.
1.It is a universal solvent.
2Pure water is transparent, colourless and odourless.
3.Pure water is a poor conductor of electricity.
4.Water in a pure form has a neutral ph i.e 7 which means it is neither acidic nor basic.
An onion cell has a rectangular shape
