The researchers introduced a small RNA complementary to a portion of the mRNA encoding protein A into the Brec-MUT cells growing
in a petri dish. The researchers claim that the treated cells will fail to stimulate blood vessel formation. Based on information provided, provide reasoning to support their claim.
Delivered small RNAs can inhibit protein A production through the RNA interference (RNAi) mechanism, and thus impairs angiogenesis
Explanation:
The pregnancy-associated plasma protein-A is a protease enzyme involved in the formation of new blood vessels by increasing insulin-like growth factor I (IGF-I) bioavailability. Moreover, small RNAs (<200 nucleotides in length, generally 18 to 30 nucleotides) are non-coding RNA molecules that function in RNA silencing through the RNA interference (RNAi) pathway. Small RNAs are widely used in molecular biology laboratories because they can be delivered into specific cells in order to silence target mRNAs such as, in this case, the mRNA encoding protein A, by complementary base pairing and thereby inducing translational repression. In consequence, mRNAs complementary to delivered small RNAs are silenced through RNAi pathways, i.e., by cleavage of the target mRNA and/or mRNA destabilization.
<span>Their electrons are far away from the nuclei of the atoms. Transfer high-energy electrons from NADH and FADH2 to protein complexes of the electron transport chain. </span>
The answer for the given question above of "which the Earth spheres does the process of weathering most affect", is Geosphere. <span>Geosphere weathers the rocks and all things with rocks. I hope this answer helps.</span>
