Loop Diuretics
These are diuretics that exerts effect on the loop of Henle. They are primarily used in heart failure, hypertension and edema. In contrast with Thiazides, loop diuretics are more effective in patients with abnormal kidney function. Loop diuretics inhibit the magnesium and calcium reabsorption in the thick ascending limb of Henle. Loop diuretics is highly protein bound. It has volume of distribution that is limited. This causes the diuretics to be secreted in the convuluted tubules to exert its function.
Electricity is caused by moving particles that have either a negative or postivite charge
Because the molecules that are being transported is moving against its concentration gradient. in other words, its moving from where its low in concentration to where its high in concentration
