Development of cognitive instruments for use in clinical trials of antidementia drugs:Alzheimer's Disease Assessment Scale (ADAS).
What is Alzheimer's Disease Cooperative Study?
The Alzheimer's Disease Cooperative Study (ADCS) cognitive assessment procedure was created to investigate the validity and reliability of cognitive assessment tools that could be useful additions to the Alzheimer's Disease Assessment Scale (ADAS) or other short batteries used in antidementia medication studies. Patients with mild to moderate AD and elderly individuals with normal cognitive function underwent a battery of five tests at least three times over the course of a year as part of an overall ADCS protocol to create new instruments for use in clinical trials of treatments for Alzheimer's disease (AD). The main result of this inquiry was the discovery of certain prospective additions to the current ADAS that broaden the scope of the cognitive domains and symptom severity levels addressed.
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Answer:
Explanation:
Their course of action in altering metabolism is very similar because both of them interact with intracellular receptors (primarily the cytosolic receptors present in cytoplasm of the cell) and translocate into the nucleus for performing their desired goal (likely to synthesize a mRNA which can then be turned into a protein to get a desired action going)
The law is the USA Patriot Act that gives law enforcement agencies greater power to monitor electronic and other communications with fewer checks.
The USA PATRIOT Act aims to prevent and punish acts of terrorism both domestically and abroad, as well as to improve law enforcement's investigative resources, which include:
1. to improve U.S. efforts to stop, uncover, and prosecute international money laundering and terrorism funding;
2. to provide foreign financial institutions, foreign governments, and groups of international transactions that might be abused by criminals additional scrutiny;
3. requiring possible money laundering to be reported by all eligible financial services industry participants;
4. In order to expedite the return of stolen assets to their rightful owners—countries whose citizens they originally belonged—and to tighten policies that prohibit corrupt foreign officials from using the U.S. financial system for personal advantage,
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Answer: Option A. "Cytoskeleton"
Explanation:
Cytoskeleton can be defined as the network of protein filaments in the cytoplasm eukaryotic cells interlinking from cell nucleus to cell membrane.
There are three basic types of protein fibers present in cytoskeleton that includes micro filaments (Actin filaments ), microtubules and intermediate filaments.
Microfilaments are consist many linked monomers of a protein known as actin, that combines in a double helix with a diameter of about 7 nano-meter and functions as serving tracks for myosin (motor protein).
Microtubules are arranged in a form of hollow straw like structure made up of consist of tubulin proteins having diameter of about 25 nano-meter and further consist of two subunits, α-tubulin and β-tubulin.
Intermediate filaments are the cytoskeletal element which are made up of multiple strands of fibrous proteins wounded together having an average diameter of 8 to 10 nano-meter.