Answer:
1. Integrity
2. Health Care
3. Code of Ethics
Explanation:
I calculated it logically
Answer:
Explanation:
avid experienced his first bout at around 12 years old. At first, it was uncontrollable crying, not wanting to get out of bed and go to school, and feelings of worthlessness. He was more sensitive than ever about being “left out.” But even with these feelings, he remained the consummate perfectionist. For example, anything less than an “A” in school would prove to David that he was a worthless person. Now at 18, David’s grades are dropping quickly. He can’t eat; he can’t sleep. The pain he suffers day
Answer: The next most appropriate step would be a LUMBAR PUNCTURE.
Explanation:
A LUMBAR PUNCTURE is a medical procedure that is usually carried out by a trained health personnel. It is a procedure that is carried out in the lumbar region of the spinal cord to access and obtain the cerebrospinal fluid which is used for further diagnosis of an underlying disease or illness.
A LUMBAR PUNCTURE is often adviced when the symptoms of a disease is related to the central nervous system. From the symptoms observed from the 19-year-old woman at the emergency department which includes:
--> generalized headache which is increasing in intensity,
--> blurred vision,
--> intermittent diplopia,
--> vague dizziness.
--> bilateral papilledema and
--> normal MRI of the brain.
Since the MRI of the brain is normal, the most appropriate step to be taken by the health care provider is a lumbar puncture which enables a direct access to the cerebrospinal fluid. This would help to rule out an elevated intracranial pressure which may be the cause of the generalized headache which is increasing in intensity.
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
