Punnett squares provide an easy way to predict the possible genotypes for an offspring, but it is not practical to perform a Pun
nett square analysis on all possible combinations of all members of a population to predict what the population might look like in the future. a. True
b. False
There are certain limitations associated with the Punnett Squares. They are not useful in case of complex genetic inheritance such as linkage between two genes. In case of linkages it becomes difficult to estimate the distribution of genotypes and phenotypes. For example in case of Nail-patella Syndrome and gene associated with blood group two genes lie on the same chromosome in close vicinity and hence there are high chances of inheritance of these traits in the offspring from the parent thereby causing random distribution of the two traits. This random distribution cannot be captured through punnet square.
The same problem is associated in case where a single gene is determined by multiple genes with graded effects of each gene.
