If the product of both of these two numbers needs to be a negative45 then there are no pair of integers that comply with both requirements.
If the multiplication in the question is wrong and it is a positive 45 then the pair of integers that would comply with these requirements would be (3 and 15). Multiplying this pair together would give you 45 and the difference between them is also 12 meaning it complies with both requirements that were asked for in the question.
