Traditional chemotherapy drugs target cell metabolic processes which enabled it to thrive under certain conditions and then halts such processes such as cell division or results in cell death.
Thus, these drugs are cell poisons, causing multiple side effects. Some of the other cell processes that these cells target also include replication and motility.
The role of the nucleolus is to make the monomer of of ribosomes, and ribosomes are used in mRNA to make protein. Therefore the nucleolus plays a major role in the process of making proteins for our body. <span />