Answer:
Causes
The institution of the Spanish Inquisition was ostensibly established to combat heresy.
The Spanish kingdom was unified with the marriage of Ferdinand II and Isabella I, and the Inquisition served to consolidate power in the monarchy.
The desire for religious unity in the Iberian Peninsula increased toward the end of the Reconquista, a series of campaigns by Christian states to recapture territory from the Moors.
Anti-Semitism had grown toward Spain’s Jewish community during the reign of Henry III of Castile and Leon, and pogroms had forced many to convert to Christianity.
Marranos, those who had converted from Judaism to Christianity but continued to practice their faith in secret, were increasingly considered a threat to Spanish society. Spaniards were concerned with the idea of limpieza de sangre (Spanish for “purity of blood),” which the presence of even baptized Jews threatened.
The religious fervor of the Catholic Monarchs also led to the persecution of Muslims and Protestants.
Effects
Hundreds of thousands of Spanish Jews, Muslims, and Protestants were forcibly converted, expelled from Spain, or executed.
The Inquisition spread into other parts of Europe and the Americas.
Mandatory conversion to Roman Catholicism and expulsion from Spain’s territories of people from other religious traditions resulted in a more homogenous Spanish culture.
The power of the Spanish monarchy increased.
Spain was deprived of many economically active citizens and suffered financially compared to other European powers.