Answer:
Potential targets:
1- DNA methyltransferases
2- Chromatin modifiers such as histone acetyltransferases, histone deacetylases, histone methyltransferases, etc.
3- Components of the RNA interference (RNAi) machinery such as Dicer, Argonaute, etc.
Explanation:
Epigenetics can be defined as the study of any heritable change in the phenotype that does not involve modifications in the DNA sequence. Epigenetic mechanisms can be classified into three major types: 1-DNA methylation, 2-histone modifications (e.g., acetylation, methylation, phosphorylation, etc), and 3-regulatory non-coding RNAs (e.g., miRNAs, lncRNAs, siRNAs, etc) that modulate target gene expression via the RNA interference pathway. There are different types of proteins that are involved in these complex epigenetic mechanisms, and those cited above represent only some examples that can be used as therapeutic targets.
Answer:
Mechanisms are activated where it is sought to lower the amount of free protons in the blood, that is, to reduce acidity, these mechanisms work between two large systems, the receptor system, the respiratory system and the renal system.
Explanation:
When a metabolic acidosis is entered, either by a food, or by a disease or even an intense physical activity, the lungs seek to generate hyperventilation, to increase the concentrations of oxygen in plasma and absolutely decrease the carbon dioxide concentration, thus not the blood becomes even more acidic.
On the other hand, the digestive system together with the sensory system, will warn this proprioception of the acidity of the plasma and will promote the dilution of these acids with a solvent, which is water, promoting the sensation of thirst.
Finally, the kidneys will seek to retain all the alkaline solutes to neutralize the physiological internal pH, and will release through the urine and the channels of acidic compounds, the products or acid metabolites to the external environment, that is, acid urine excretion.
Allegedly, <span>the finger tips show where the wind blew when our ancestors were created. In a way, their fingertips are roots to their ancestors, so touching them somehow links them to their ancestors. And as you probably know, the Navajo are very much connected to their ancestors, and tribes in general. </span>
Summary. Cellular respiration is the aerobic process by which living cells break down glucose molecules, release energy, and form molecules of ATP. Overall, this three-stage process involves glucose and oxygen reacting to form carbon dioxide and water
Volume= length*width*depth
depth=Volume/(length*width)
d=2500/(40*22)
d= 2500/880
depth=2.841ft hope this answer helps you
