Answer:
If a proto-oncogene's gene product is produced in smaller quantities, a cell may become cancerous.
Explanation:
The transformation of a cell to a malign cell occurs by mutations accumulation in some specific genes. These genes are grouped into two groups or families:
- Protooncogenes
- Tumor suppressor genes
Protooncogenes direct the production of proteins of varying locations and functions that play a significant role in cell proliferation and differentiation. The proteins include cyclins, growth factors, receptors, etcetera. These genes are proteins codifiers and influence the cell cycle by favoring proliferation or inhibiting senescence and apoptosis.
Depending on the organism´s development stage, these genes can be physiologically active or reprimed.
Certain structural or functional changes in protooncogenes contribute to turning them into oncogenes. When protooncogenes mutate into oncogenes, they are capable of controlling cell multiplication and massively synthesize uncontrolled division triggers.
