Local anesthetics inhibit nerve conduction in a reversible manner without altering the nerve. The inhibition appears rapidly and for a longer or shorter duration depending on the products and the concentrations used. The extent of the territory rendered insensitive to pain depends on the modes of administration of the local anesthetic, either at the level of the nerve endings, or at the level of a nervous trunk, for example.
They act at the level of the neuronal membrane by interfering with the process of excitation and conduction. The anesthetic crosses the axon membrane, rich in lipids, in the form of base before taking up a cationic form on the internal face of the neuron where the pH is more acidic.
At this level, there is a blockage of nerve conduction by decreasing the membrane permeability to sodium ions that occurs during the depolarization phase. As the progression of the anesthetic action along the nerve increases, the threshold of excitability increases and the conduction time increases. This is completely blocked from a certain concentration of local anesthetic.
The nerve fibers are unequally sensitive to the action of local anesthetics: they disappear in order: the painful, thermal, tactile sensations.
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Answer: Zoonosis
Explanation: Rabies, the plague, and West Nile virus are transmitted through a bite from an animal that is infected. Not sure if anthrax is transmitted through a bite as I just know you just need to come in contact with an animal who has it.
West Nile comes from mosquito bites, rabies from any rodent, canine, mammal, ECT, and the plague originally came from rats who had the black plague.
I hope I helped bud.
What are the different answers?
