Monoclonal antibodies are made by the fusion of cells of the immune system with B lymphocytes and myeloma cells.
<h3>What is Hybridoma technology?</h3>
- It is one of the best technologies that is used to produce the monoclonal antibody.
- In this hybridoma technology the B lymphocytes that are antibody producing are isolated from a source after the immunization with a specific antigen and then are fused with myeloma cell line to form hybrid cells that are also called as hybridoma cell lines.
- The hybridoma cell lines are then cultured in the laboratory with specific antigen and then the monoclonal antibodies are produced.
- This can be done in in-vivo or in-vitro condition.
- This method is preferred over all because the production of antibodies by this method is good as the antibodies produced are of high purity and highly sensitive and specific.
- These cell lines can also be preserved for a long time.
- Hybridoma technology has resulted in production of different varieties of monoclonal antibodies with specificity with specific antigens as the monoclonal antibodies are produced by single parental B cells.
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I think true if its not sorry
Explanation:
In addition, in meiosis I, the chromosomal number is reduced from diploid (2n) to haploid (n) during this process. ... In humans (2n = 46), who have 23 pairs of chromosomes, the number of chromosomes is reduced by half at the end of meiosis I (n = 23).
