<span>Canagliflozin is a recently discovered drug that is used in the treatment of type 2 diabetes, by inhibiting SGLT2 transporters in kidneys that reabsorb glucose from the urine.
EFFICACY:
Cohort studies were made to compare canagliflozin to other molecules (glimepiride and sitagliptin) by evaluating the life quality, weight and </span>HbA1c (glycated hemoglobin) for 52 weeks. it was found that canagliflozin has a better efficacity and a better effective cost ratio.
SIDE EFFECTS:
The most frequent side effects are constipation, thirstiness, nausea, and headache.
Due to its mechanism of action, a high glucosuria can be found also.
Severe complications can occur, like euglycemic ketoacidosis. This drug has a high amputation and risk (like other SGLT2 inhibitors) and a high fracture risk (due to the diminution of the mineralization of the bones).
One "fact" that is false about testosterone, is that some believe women do not need testosterone as part of their hormones. Alas, women do require testosterone, as without it, can cause numerous dilemmas with their health. For instance, a gain in body fat.
Lipids-fats, wax. oils, phospholipids, steroids
carbohydrates-sugars( glucose, glycogen, and cellulose in plants), starch
proteins- amino acids, and enzymes
nucleic acids- RNA, DNA
Correct answer:
"All of these are equally affected."
When in Alzheimer's disease, all of the working memory is in peril. In early stages of Alzheimer's disease, all of these functions start to have problems. Phonological loop is basically the capacity to memorise speech or information in it. Central executive is the ability to switch attention from one activity to another that is needing more attention. The visuospatial sketch pad is the ability to handle visual and spatial information being able to judge distances for example. All of these are part o the working memory and are affected from the early stages of Alzheimer's disease.
