Answer:
c. Major groove
Explanation:
The interaction surfaces of proteins are, in general, varied. From the point of view of the secondary structure, the surfaces of the proteins are formed by the surfaces of their α helices, β sheets and loops that conform them. The surfaces of the DNA molecules are less varied: the B-DNA helix has a monotonous “screw” shaped surface with phosphoribose ridges between which two grooves (major and minor) are formed. The difference between different nucleotide sequences can only be seen from outside in the major groove, where the bases appear. The surfaces of RNA molecules that possess tertiary structure (such as t-RNA) are almost as complex as that of proteins.
Since the major groove is the only site where the bases are accessible from outside the B-DNA without distorting it, the major groove constitutes the main recognition site. As the interaction between molecules is stronger if their surfaces are complementary, the protein-DNA interaction usually occurs by filling the major groove.
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Answer:
The probability that both will be Rh-negative out of 99% Rh-positive is 0.01 x 0.01 = 0.0001.
Explanation:
The population contain 99℅ of Rh-positive. This represent almost all of the people.
However, there is still 1℅ chance of having an individual of Rh-negative.
Both of them will have the probability of 1℅ of having Rh-negative(0.01).
Therefore, Pr(Rh-negative AND Rh-negative) = 0.01 x 0.01. The result is approximately equals zero.
The both parents having Rh-negative, will have a dominant Rh-negative blood passed to their children, only recessive Rh-positive of 25℅ chance.
Since the chance of Rh-negative blood passed to their children is 75℅, it is inevitable that their children will be Rh-negative
Answer:
B. an amino terminal signal peptide
Explanation:
The reactions of the citric acid cycle occur in the matrix of mitochondria. Therefore, all the enzymes required for this pathway are present in the matrix of mitochondria. These enzymes are formed on the ribosomes present in the cytosol and are transported into the mitochondria with the help of cytosolic heat shock proteins. The newly formed mitochondrial proteins have signal sequences present at their N terminal. The proteins to be transported into the matrix have a single signal sequence that at N terminal which is removed by a protease once the enzyme enters into the matrix.
