I think causing a physical change
2 in the first and remaining 4 in the (outer) shell
Answer:
It will be on the cytoplasmic side of the endoplasmic reticulum
Explanation:
The inner mitochondria protein called Adenine Nucleotide Translocator or ADP/ATP carrier protein, maintains the transport of ADP into the matrix of the mitochondria from the cytoplasm for ADP to be available for ATPase synthesis of ATP, from ADP and Pi(inorganic phosphate ion) during chemiosmosis of oxidative phosphorylation in the mitochondria.
The same carrier proetin also convey the synthesized ATPs back to the Cytoplasm for cellular utilization.
Therefore the ATP binding site should at the cytoplasmic side of the E.R, because the cytoplasm of the E.R is the site of deposits of synthesized ATP s, thus proximity of the ATP-binding site to it is needed.
They are called circadian rhythm. Circadian rhythms are physical, mental and behavioral changes that follow a repeated daily cycle. They are usually biological processes that display an oscillation of about 24 hours and occurs in animals, plants and even cyanobacteria. The process responds to changes in light and darkness in the surroundings of an organism.