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DanielleElmas [232]
2 years ago
7

As the most junior member of a lab, you are tasked with generating cell lines that accumulate DNA damage to investigate how rand

om mutations affect transformation of cells into cancer cells. You decide to mutate proteins in the p53 pathway. Which three proteins would you mutate
Biology
1 answer:
34kurt2 years ago
5 0

Answer:

In p53 pathways, 3 proteins which are mutate and cause cancer that proteins are:

1.BRCA2  

2. p53 in Rb genes binds with deoxyribonucleic acid that stimulates another gene to produce a protein known as p21 that interacts with cdk2. When p21 is combined with cdk2  cell will not pass through to the next stage of cell division. This is Li-Fraumeni syndrome (when p53 causes cancer from parents to offspring)  

3.BRCA1  

The parent that transmits mutation in one of these genes has a 50% chance of inheriting the mutation. The effects of mutations in BRCA2 and BRCA1 are seen when the person's second copy of the gene is normal.

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Explanation:

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Their structural components (i.e. their makeup) determine their function (what they do). In specific cell types, collected proteins may function as a unit called an organelle. Some organelles are bound by membranes like those that make up the external structure of the cell, with varying compositions of phospholipids and proteins. Several organelles facilitate the digestion of nutrients into metabolites and energy...

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Learn more about cellular life at brainly.com/question/11259903

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