Answer:
transcription initiation
Explanation:
Transcription is a process by which genetic information from DNA is used to synthesize an RNA molecule, usually, a messenger RNA (mRNA), which is subsequently utilized to synthesize a protein by a process called translation. Transcription in prokaryotes has three steps:
1-Initiation: the RNA polymerase is a multisubunit enzyme (holoenzyme) composed of two α, one β, one β’ and one ω and σ subunits (α2ββ’ωσ). This holoenzyme binds to the promoter region of the template DNA strand.
2-Elongation. The sigma σ factor of the holoenzyme is released and the complex and the core enzyme (α2 ββω) moves along the template strand, thereby producing an mRNA sequence
3-Termination. This step can be Rho-dependent, where a protein named "Rho" recognizes the termination site and stop transcription, and Rho-independent (transcription continues until the termination sequence is reached).
In consequence, Rifamycin is likely to block the initiation of transcription because the core RNA enzyme needs to bind the sigma factor (σ) for initiation of transcription in bacteria.
Chemotherapy and/or stem cell transplant
Close the yield gap. By 2050, 120 million hectares of natural habitats will be converted to farming in developing countries, the World Wildlife Fund estimates. ...
Use fertilizer more efficiently. ...
Raise low water productivity. ...
Target food for direct consumption. ...
Reduce food waste.
