Answer and Explanation:
The manipulation of the gene is called genetic engineering. In genetic engineering, fragments of genes are cloned by leading the genes into the host cell. The advantage of using a prokaryotic host system in genetic engineering is that bacterial cells are used to produce commercially significant products. For example, human growth hormone helps to treat dwarfism, and human insulin production, which is used to treat diabetes. The bacterium P.putida is created by genetic engineering, which is used to break down petroleum products. Genetic engineering also carries some potential risks, such as transferring the selected gene into another speice, benefit one species can harm another speice. Therefore genetic engineering must be used in limit in prokaryotes. These limitations are also addressable in single-cell eukaryotic systems. Biologics-based therapeutic medicines such as a vaccine, gene therapies, and cell therapies known as bioproduction are produced. Medicines are so complex that they can only be formed in a living system. Biopharmaceuticals, value-added food, fuels, chemicals, antibiotics, and many other products are produced by bioproduction.
DNA<span> and </span>RNA<span> are nucleic acids found in the cells of living organisms. ... The </span>synthesis<span> of </span>proteins<span> starts with transcribing the instructions in </span>DNA<span> into mRNA. The mRNA is then carried out of the cell's nucleus into the cytoplasm, specifically into structures called ribosomes.</span>
Two of these options are correct (A & E)
So, the correct option is D.
<h3>About ADH/Vasopressin:</h3>
- Other name for ADH is arginine vasopressin.
- It is a hormone produced by the brain's hypothalamus and kept in the posterior pituitary gland.
- It instructs the kidneys on how much water to hold onto.
- The amount of water in your blood is continuously regulated and balanced by ADH.
- Your blood's volume and pressure increase with higher water concentration.
- ADH helps to sustain water metabolism along with osmotic sensors and baroreceptors.
- The concentration of particles in your blood causes osmotic sensors in the hypothalamus to respond.
- Carbon dioxide, sodium, potassium, chloride, and other chemicals are among these particles.
- These sensors and baroreceptors tell your kidneys to store or release water to maintain a healthy range of these substances when particle concentration is out of balance or blood pressure is too low.
- They also control how thirsty your body feels.
- The particular nerve cells that make anti-diuretic hormone are located in the hypothalamus, a region at the base of the brain.
- The hormone is sent by the nerve cells to the posterior pituitary gland, where it is released into the bloodstream, via their nerve fibers (axons).
- By influencing the kidneys and blood arteries, anti-diuretic hormone aids in maintaining blood pressure.
- Its primary function is to decrease the volume of water excreted in the urine, so conserving your body's fluid volume.
- This is achieved by permitting a specific region of the kidney to enable water from the urine to be reabsorbed into the body.
- As a result, the bloodstream is replenished with more water, urine concentration increases, and water loss is decreased.
<h3> Aquaporins and ADH:</h3>
- Antidiuretic hormone levels above a certain threshold narrow (constrict) blood arteries, raising blood pressure.
- The only way to fully recover from a lack of bodily fluid (dehydration) is by drinking more water.
- The aquaporin 2 protein is made according to instructions from the AQP2 gene.
- The water molecules are transported across cell membranes by this protein, which creates a channel.
- Collecting ducts, a network of tiny tubes that reabsorb water from the kidneys into the bloodstream, are found in the kidneys where it is discovered.
- In order to keep the body's water balance in check, the aquaporin 2 water channel is crucial.
- A hormone known as vasopressin or antidiuretic hormone regulates the positioning of these channels (ADH).
- The body creates more ADH when the amount of fluid consumed is low or when there is a lot of fluid loss (for instance, through sweating).
- Aquaporin 2 water channels are ultimately inserted into the membrane of collecting duct cells by this hormone, which sets off chemical events.
- Due to the re-absorption of water into the bloodstream made possible by these channels, the urine is more concentrated.
- Less ADH is created when fluid intake is sufficient. Aquaporin 2 water channels are taken out of the collecting duct cells' membrane in the absence of signals from ADH.
- During these times, the urine is more diluted and less water is reabsorbed into the bloodstream.
Disclaimer: The given question was incomplete on the portal. Here is the complete question.
Question: ADH or Vasopressin...
A. Promotes the insertion of aquaporins (specifically AQP2) into the apical membrane of the collecting duct cells
B. Promotes the insertion of aquaporins (specifically AQP3 and AQP4) into the basolateral membrane of the collecting duct cells
C. All of these options are correct
D. Two of these options are correct
E. When released, increases the osmolarity of the excreted urine
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Answer: a) substrate and cofactors b) covalent modification
Explanation:
Metabolic pathways involve all the chemical processes takes place in the enviornment or in an organisms.The metabolic pathways are controlled through the catalytic activities of enzymes.
The availability of enzyme is regulated by substrate and cofactors present in enzyme and enzyme activity is commonly regulated via covalent modification.
Enzymes are highly selective in nature and bind to a specific substarte only. The active site in enzyme binds with the substrate to form enzyme substrate complex. Coactors assist the enzyme activity, without cofactor enzyme can not perform its activity.
Hence enzyme availibility is regulated by substrate and cofactors regulates.
Covalent modifications regulates activity of enzyme as it involves addition and removal of chemical group to synthesis required protein. It can change the chemical properties of the site by targeting one or multiple amino acid.
Thus the correct answer is a) substrate and cofactors b) covalent modification
