Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
Reduce osteoblast activity while boosting osteoclast activity
osteoblast:
- Untreated celiac disease has a number of potential side effects, including the failure for children to reach their ideal bone density and adult bone loss, both of which raise the risk of osteoporosis. Following a gluten-free diet is the only way to treat celiac disease.
- As a result, celiac disease is common in both children and adults with low bone density. When celiac disease is discovered in an adult, the risk of osteoporosis is very significant (because they have gone longer without absorbing enough calcium and other nutrients).
- Osteoporosis is a bone disease that appears when bone mass, bone mineral density, or both drop or when the quality or structure of the bone deteriorates. This may result in a loss of bone density and an elevated risk of fractures (broken bones).
Learn more about osteoporosis here brainly.com/question/14601010
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22. D, that means the soil uhhhh helps the roots to grow??? Also because sunlight causes photosynthesis- sorry i’m not good at this hope it helps
Your answer is D, Rhizobium
Energy is lost at each Trophic level of a food chain. The more levels then the more energy lost to those at the top.
