Answer:
usually ppl with diabetes two make insulin with their body neither way the bodt doesn't rreally respond good to the body mking it which then means that glucose is less able to enter the cells and make energy. neither way it because glucose can't eneter the cells the doctors call it insulin resistance.
Explanation:
Answer:Misdemeanors in New York are divided into 3 classes: Class A misdemeanors, Class B misdemeanors, and unclassified misdemeanors.
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:tools
Explanation:because we use them so it can help us
Answer:
Resting metabolic rate is a measurement of the number of calories that your body burns at rest. Resting metabolic rate is usually measured in the morning before you eat or exercise and after a full night of restful sleep. Basal metabolic rate (BMR) is a measurement of the number of calories needed to perform your body’s most basic ( basal) functions, like breathing, circulation and cell production.
