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ValentinkaMS [17]
2 years ago
6

In the disease myasthenia gravis, the human body makes-by mistake- antibodies to its own acetylcholine receptor molecules. These

antibodies bind to and inactivate acetylcholine receptors on the plasma membrane of muscle cells. The disease leads to devastating progressive weakening of the muscles of people affected. Early on, they may have difficulty opening their eyelids, for example, and, in an animal model of the disease, rabbits have difficulty holding their ears up. As the disease progresses, most muscles weaken, and people with myasthenia gravis have difficulty speaking and swallowing. Eventually, impaired breathing can cause death. Explain which step of muscle function is affected
Biology
1 answer:
andre [41]2 years ago
6 0

Answer:

Muscle contraction function.

Explanation:

The nerve endings possess synaptic acetylcholine vesicles ready to be released. The action potential depolarizes the presynaptic terminal and increases the concentration of axoplasmic calcium; Acetylcholine molecules are thus released, so that the concentration of the neurotransmitter at postsynaptic (nicotinic) receptors is temporarily increased. This is followed by post-synaptic membrane depolarization, muscle membrane action potential with increased rnioplasmic calcium concentration, and finally muscle contraction. Acetylcholine is hydrolyzed by acetylcholinesterase and resynaptic at the presynaptic level by cholinecetyltransferase. The etiopathogenesis of myasthenia gravis is autoimmune and there are antibodies against acetylcholine receptors that circulate in the blood, as well as a decrease in the number of receptors on the motor plates, that is, it is produced by the postsynaptic blockage of the myoneural plaque, that generates fatigue and localized or generalized muscle weakness that is characterized by the worsening of the contractile force of the muscle.

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Read each description below regarding innervation of the ANS. Then click and drag each into the appropriate category base on whe
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The question is incomplete. Here is the complete question.

Read each description below regarding the dual innervation of the ANS. Then click and drag each into the appropriate category base on whether it is an example of antagonic or cooperative innervation.

The sympathetic division stimulates mucus production by salivary glands while the parasympathetic division stimulates enzyme secretion.

The sympathetic division stimulates am increase in heart rate while the parasympathetic division stimulates a decrease in heart rate.

During sex, the parasympathetic division stimulates arousal while the sympathetic division stimulates orgasm.

The parasympathetic division constricts the pupils while the sympathetic division dilates the pupils.

Antagonistic:

Cooperative:

Answer: <u>Antagonistic:</u> The sympathetic division stimulates am increase in heart rate while the parasympathetic division stimulates a decrease in heart rate; The parasympathetic division constricts the pupils while the sympathetic division dilates the pupils.

<u>Cooperative:</u> The sympathetic division stimulates mucus production by salivary glands while the parasympathetic division stimulates enzyme secretion.; During sex, the parasympathetic division stimulates arousal while the sympathetic division stimulates orgasm.

Explanation: The peripheral nervous system is divided in <u>Somatic Nervous System (SNS)</u> and <u>Autonomic Nervous System (ANS)</u>. The first is responsible for sensory input and voluntary motion.

Autonomic Nervous System is divided into <u>Sympathetic and Parasympathetic divisions</u> and is controls the fight-or-flight and rest-and-digest situations. Usually, an organ with sympathetic and parasympathetic innervations have antagonic function, such as the heart rate -  one system causes the heart rate to increase while the other stimulates the rate to decrease. However there are cases in which the combination of the 2 systems cause an increase of stimulation, producing similar effects.

Analysing each category above, it is deductable that when the sympathetic stimulates mucus production and parasympathetic, enzyme secretion and when the parasympathetic stimulates arousal and sympathetic, orgasm, in both cases, they have cooperative innervation.

On the other hand, when sympathetic stimulates increase in heart rate and parasympathetic, decrease in the rate, as stated before, and one stimulates constriction of the pupils and the other, dilation of the them, those are examples of having antagonic innervation.

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