He sought to do nothing that would upset the neutrality of the border states of Missouri, Kentucky, Maryland, and Delaware
He attempted to force a decision upon southern states that had seceded. Placing them in a position to be futility of causing the war which be repeatedly declared he did not want..
It shortened the travel time and distance and improved trade.
They both caused a lot of Native Americans to be wiped-out from diseases, that they brought to the new world.
