Ummm. It's simply not a question l. "How not to be lonely." Is a statement. Like, this is how not to be lonely.... if it were to be a question then you would say, "How do you not be so lonely?"
Answer:
<em>Antibodies attach to a specific antigen and make it easier for the immune cells to destroy the antigen. T lymphocytes attack antigens directly and help control the immune response. They also release chemicals, known as cytokines, which control the entire immune response</em><em>.</em>