The first 4 digits are simple, you multiply the first digit of the equation by the 2nd digit and then for the other 2 you multiply the first digit of the equation by the 3rd digit.
6 + 2 + 8
6 * 2 = 12
6 * 8 = 48
Then the last 2 digits are the sum of the products of the 1 and 2 and 1 and 3 and subtract it by the 2