Columbus and his men encountered indigenous people
Both the Southern and Middle Colonies had fertile farmlands, but only the Middle Colonies was able to provide trading opportunities, thanks to their coastal lowland and bay-provided harbors. Southern Colonies highly contributed to the rise of cash crops such as rice, tobacco, and indigo. Slaves cultivate huge tracts of land and plantations owned by wealthy aristocrats and large landowners. On the other hand, Middle Colonies were more suitable for growing grain and livestock, with its environment ideal for small to large farms. More diverse workforce also exists in the Middle Colonies, consisting of farmers, fisherman, and merchants. Another notable contrast between the two colonies is that, for the people of the South, life developed as rough and rural while people of the Middle countries are deeply connected to the Church and village community.
C I’m pretty sure tho C. Lol
William Penn and Roger Williams, that is the correct answer TRUST ME I TOOK THE QUIZ AND TE ANSWER BELOW ME IS WRONG!
The answer is slavery. The Republicans were anti-slavery, while the democratic south was pro slavery. Eventually that, and a couple of other things, led to the Civil War.
Sorry if this was a bit late, Brainly had just recommended this question for me to answer, but I hope this helps!