Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Answer:
B
Explanation:
Two molecules of ATP from the cell are invested at the beginning of the process of glycolysis.
Answer:
The correct answer is - Transcribing information in the DNA sequence for use by the cell.
Explanation:
The transcription process is the process that involves copying the sequence of DNA, that sequence is the information or code for the particular protein, to make RNA molecule that brings the information to the ribosome where translation process initiated to produce amino acid chain.
In the given diagram, the cellular process is showing is transcription as there is transcribing the sequence is shown which copy the sequence that is used for the cell and a useful part of protein synthesis
<span>During Michelle's 6th month of pregnancy, the eyes, ears, and nose form.</span>
I would just recommend looking up a diagram of a cell, that should help and you should get all the necessary answers
