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Sickle cell anemia results from a mutation in a gene called HBB, which contains the blueprint for cells to make part of a protein called hemoglobin. The hemoglobin protein is made up of two alpha chains and two beta chains.
Sickle cell anemia is the result of a point mutation, a change in just one nucleotide in the gene for hemoglobin. This mutation causes the hemoglobin in red blood cells to distort to a sickle shape when deoxygenated. The sickle-shaped blood cells clog in the capillaries, cutting off circulation.
Montreal Protocol is the correct answer I think
The answer is "Starbucks"
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This can be caused by mating differences, sterility or environmental barriers that eventually lead to the adaptive splitting into two species. ... However, reproductive isolation is not sufficient but internal barriers to gene flow are required for speciation to evolve.
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I hope this helps I'm not so good at explaining.