Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
To learn more about stroke with the help of given link:
brainly.com/question/26482925
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Explanation:
Nys Shabie
PO Box 735,
Mukono.
4th October,2021.
To the Minister of health,
PO Box 1112,
kampala.
Dear Sir,
THE OBSERVATION AND CONTROL OF INREASE OF MALARIA.
Dear sir,i have written this letter to kindly explain and seek for your help about the high increase of malaria in our town.it has been now four year of death caused by malaria.
Many people are now in caos and so Sir we need your help.
Hopefully alot of people are willing to collaborate with all means of how to control malaria.we came up with education about causes and control of malaria to people and are willing to take action if at all they are given support
We kindly request for chemicals to put in dirty pits,in stagnat water,and we need slashers to cut the grass that have bacome home for the mosquitoes.
Am looking forward to recieving your kind reply
yours sincerely,
Nys_bie.
Nys Shabie.
Answer:Hand hygiene.
Use of personal protective equipment (e.g., gloves, masks, eyewear).
Respiratory hygiene / cough etiquette.
Sharps safety (engineering and work practice controls).
Safe injection practices (i.e., aseptic technique for parenteral medications).
Sterile instruments and devices.
Clean and disinfected environmental surfaces.
Explanation:
Answer: HDLs are antiatherogenic lipoproteins....
Explanation:
The anti-atherogenic effect of HDL occurs, above all, because of its properties to carry lipids, mainly cholesterol esters from peripheral tissues to the liver, which is known as reverse cholesterol transport(RCT). However, other protective actions of HDL, in addition to RCT, have been described in several experimental models and epidemiological studies. These actions include antioxidant protection, mediation of cholesterol efflux, inhibition of the expression of cell adhesion, leukocyte activation, regulation of blood coagulation and platelet activity.
